FWIW (I have an R1 version but the idea is the same)-
Yes, I was able to thread a tie wrap though similar holes in the bed support plate.
I used a smaller profile (but long enough) tie wrap, and threaded it through before attaching the build plate.
I also used an adhesive tie block to further secure the wiring (I always keep those around) and ran the wires through the front large cutout (not sure what is front in your picture), which as I recall was backwards from what the build manual of that time showed.
To do that, and to make the wire bundle coiled neatly underneath I had to extend the thermistor wires by around a foot using some of the extra wire clippings from elsewhere in the kit and I cut the heater wires longer than specified.
All of that went into some spare "expando" braided tubing for neatness.
I hope this helps.