I have used many hot ends on my printers and will share some of my conclusions.
On the FT-5 I upgraded to a Titan, Volcano combo and as I mentioned earlier I had a blockage issue (my fault) with the Volcano and destroyed it. I had one of the cheap clone E3D so when I pulled the Volcano out I put it in. Within a week both the heating element and the thermistor failed. I still needed something that would mount in the Titan so I took the heat sync from the clone and put a throat and Hotend that I got from Folger and this combination worked great, so well that I had the replacement Volcano for about 6 weeks before I put it it.
If you look at the whole hotend design there is not very much to it and there are very few differences. You have a heat block and about the only difference here is the size, heater elements are interchangeable (E3D used 30W while most others use 40W), not much difference in the thermistors other than how they mount, but when you get to the throat you see a lot of differences.
An all metal hot end does not mean an all metal throat. The E3D has a PTFE tube in the upper end of the throat, and the Folger throat has a PTFE tube the entire length. The cheap clone and an all metal throat and would often have partial clogs.
Heat sync design does not really matter as long as it works. The big difference is how the upper end mounts into you extruder. The extruder designs can make a big difference when using geared or 1/1 feeds. It can get a more accurate feed rate.
So with all the changes that I have made I will say that the Titan extruder made the biggest difference. The Titan with hot end from Folger - the one that came with the FT-5 with the clone heat sync so it would mount worked way better then the original design. Much smoother. I have gone back to the Volcano hotend and with the .4 nozzle you can really see any difference from the clone/Folger combo, its the Titan that made the difference. I do want the Volcano because there are time I want to push plastic faster with and without larger nozzles and the smaller heat block's can do that.
So if you have a good extruder and a well designed throat things should work well. If you are going to use a clone Volcano you might want to get a real throat to go with it ( will probably cost as much as the whole clone), but see how that one that comes with it works first. I also like a 40W heater better with the Volcano to push a lot of plastic fast.
But if you look at all the E3D clones about the only thing that really changes is the throat.